Search results for "sensitivity [detector]"

showing 10 items of 400 documents

Synthesis of the Data on COVID-19 Skin Manifestations: Underlying Mechanisms and Potential Outcomes

2021

Abstract The incidence of coronavirus disease 2019 (COVID-19)-related skin manifestations has progressively grown, in parallel with the global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreading. The available evidence indicates that cutaneous signs are heterogeneous and can be divided as follows: a) erythematous rashes, b) lesions of vascular origin, c) vesicular rashes, d) urticarial rashes, and e) acute generalized exanthematous pustulosis (AGEP), erythema multiforme (EM) and other polymorphic/atypical reactions. Most cutaneous manifestations appear simultaneously or after respiratory and/or systemic symptoms such as fever, even if rarely urticaria has been reported as…

medicine.medical_specialtycutaneous manifestationscutaneous manifestationbusiness.industrySARS-CoV-2COVID-19DermatologyDiseaseReviewmedicine.diseaseAcute generalized exanthematous pustulosisDermatologyVirusHypersensitivity reactionImmune systemmedicineskin rashesErythema multiformeRespiratory systemChilblainsbusiness
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Clozapine-related drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a systematic review.

2020

The Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a severe, multiorganic, and potentially life-threatening drug-induced hypersensitivity reaction, linked to several common drugs, including antiepileptics, antibiotics, and several psychotropic drugs, including clozapine. Due to the importance of clozapine in the management of treatment-resistant schizophrenia, a systematic review and characterization of clozapine-related DRESS syndrome is long overdue.This systematic review was conducted following PRISMA guidelines. PubMed, Embase, PsychINFO, and the Cochrane Library databases were independently reviewed up to 1 November 2019 for articles reporting clozapine-relat…

medicine.medical_specialtymedicine.medical_treatmentmacromolecular substances030226 pharmacology & pharmacyDrug reaction with eosinophilia and systemic symptoms03 medical and health sciences0302 clinical medicinehemic and lymphatic diseasesMedicineHumansPharmacology (medical)General Pharmacology Toxicology and PharmaceuticsAntipsychoticClozapineClozapinebusiness.industrymusculoskeletal neural and ocular physiologyGeneral Medicinemedicine.diseaseDermatologyHypersensitivity reactionnervous system030220 oncology & carcinogenesisDrug Hypersensitivity SyndromePolypharmacySchizophreniabusinessmedicine.drugAntipsychotic AgentsExpert review of clinical pharmacology
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A person-oriented approach to diary data. Children’s temperamental negative emotionality increases susceptibility to emotion transmission in father-c…

2015

The notion that some individuals are more prone to emotion transmission than others has prompted the need for a person-oriented approach to emotion transmission in parent-child dyads. The present study applied a person-oriented analysis to examine the patterns of emotion transmission that can be identified in the diary data of father-child dyads, and the extent to which children with high levels of temperamental negative emotionality are particularly susceptible to emotion transmission within the family. Mothers of 149 first grade children (age 6 to 7) completed questionnaires concerning their child’s temperament. Mothers and fathers maintained diary questionnaires (for a total of 7 days) c…

multilevel regression mixture model515 Psychologymedia_common.quotation_subjectlcsh:BF1-990050109 social psychologyemotionslaw.inventionDevelopmental psychologytemperamenttiPerson orientedtunteetlawnegative emotionalityemotional transmission0501 psychology and cognitive sciencesta515Applied Psychologymedia_common05 social sciencesMultilevel modelMixture regressiontemperamentdiary dataTransmission (mechanics)lcsh:Psychologydifferential susceptibility050902 family studies516 Educational sciencesTemperamentPsychology (miscellaneous)0509 other social sciencesPsychologyNegative emotionalitybiological sensitivity to contextDyadJournal for Person-Oriented Research
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Application of the Chinese Version of the BIS/BAS Scales in Participants With a Substance Use Disorder: An Analysis of Psychometric Properties and Co…

2020

Carver and White developed the Behavioral Inhibition/Behavioral Activation Scales (the BIS/BAS Scales) based on Reinforcement Sensitivity Theory proposed by Gray. Subsequent studies proposed that substance abuse was closely related to Behavioral Inhibition System (BIS) and Behavioral Activation System (BAS). However, researches on the psychometric properties of the BIS/BAS scales in clinical samples are scarce. The present study was conducted to analyze the applicability of the BIS/BAS scales in a sample suffering from a substance use disorder (SUD) and undergoing treatment in compulsory detoxification institutions (n = 1117). Meanwhile, 822 community residents were selected for comparison.…

people with a substance use disorderlcsh:BF1-990educationBehavioral InhibitionimpulsivityReinforcement sensitivity theorypsychometric propertiesImpulsivity050105 experimental psychology03 medical and health sciences0302 clinical medicineCronbach's alphamedicinePsychology0501 psychology and cognitive sciencesBig Five personality traitsGeneral PsychologyOriginal Research05 social sciencesConstruct validityBehavioral activationmedicine.diseaseBehavioral ActivationConfirmatory factor analysisSubstance abuselcsh:Psychologyself-control abilitymedicine.symptomPsychology030217 neurology & neurosurgeryClinical psychologyFrontiers in Psychology
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Thiazole Analogues of the Marine Alkaloid Nortopsentin as Inhibitors of Bacterial Biofilm Formation

2020

Anti-virulence strategy is currently considered a promising approach to overcome the global threat of the antibiotic resistance. Among different bacterial virulence factors, the biofilm formation is recognized as one of the most relevant. Considering the high and growing percentage of multi-drug resistant infections that are biofilm-mediated, new therapeutic agents capable of counteracting the formation of biofilms are urgently required. In this scenario, a new series of 18 thiazole derivatives was efficiently synthesized and evaluated for its ability to inhibit biofilm formation against the Gram-positive bacterial reference strains Staphylococcus aureus ATCC 25923 and S. aureus ATCC 6538 a…

thiazole derivativeAquatic OrganismsStaphylococcus aureusIndolesantibiotic resistanceSettore BIO/05 - ZoologiaPharmaceutical ScienceMicrobial Sensitivity TestsBacterial growthSettore BIO/19 - Microbiologia Generalemedicine.disease_cause01 natural sciencesArticlenortopsentinAnalytical ChemistryMicrobiologylcsh:QD241-441Inhibitory Concentration 50chemistry.chemical_compoundAlkaloidsAntibiotic resistancelcsh:Organic chemistryDrug DiscoverymedicinePhysical and Theoretical ChemistryThiazoleStrain (chemistry)010405 organic chemistryPseudomonas aeruginosamarine alkaloids analoguesAlkaloidOrganic ChemistryImidazolesBiofilmantibiofilm agentsSettore CHIM/08 - Chimica Farmaceuticamarine alkaloids analogueantibiofilm agent0104 chemical sciencesThiazoles010404 medicinal & biomolecular chemistrychemistryChemistry (miscellaneous)Staphylococcus aureusBiofilmsPseudomonas aeruginosathiazole derivativesMolecular MedicineMolecules
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Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy

2015

ABSTRACT A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla KPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla KPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla KPC-3 ::Tn 4401a caused by intramolecular transposition events were detected in the plasmid.

transposonsequence analysispolymerase chain reactionDrug ResistanceGene DosageSettore MED/42 - Igiene Generale E Applicatabacterial proteinbeta-Lactamaseopen reading framecarbapenemasePlasmidminocyclineplasmid DNAmeropenemPharmacology (medical)geneticscolistincefpodoximeceftazidime610 Medicine & healthCarbapenemBacterialpolymyxin Btimentingene expression regulationbacteriumKlebsiella pneumoniae carbapenemase 3 producing Klebsiella pneumoniae3. Good healthantiinfective agentmicrobial sensitivity testKlebsiella pneumoniaeItalypriority journaltigecyclineMultipleclone (Java method)cefotaxime030106 microbiologyKlebsiella pneumoniae carbapenemase 3tobramycinMicrobial Sensitivity Testsgentamicinpiperacillin plus tazobactamchemistryGene dosageArticleMicrobiology03 medical and health sciencesComplete sequenceClone CellOpen Reading FramesertapenemBacterial Proteinsmultidrug resistanceextensively drug resistant bacteriumAnti-Bacterial AgentcefepimePharmacologylevofloxacinmicrobiologycefoxitinbiochemical phenomena metabolism and nutritionbacterial infections and mycosesVirologyAnti-Bacterial Agents; Bacterial Proteins; Carbapenems; Clone Cells; Drug Resistance Multiple Bacterial; Gene Dosage; Italy; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Open Reading Frames; Plasmids; beta-Lactamases; DNA Transposable Elements; Gene Expression Regulation Bacterial; Pharmacology (medical); Pharmacology; Infectious Diseasesantibiotic sensitivityClone CellsKlebsiella InfectionsceftriaxoneCarbapenemsbacterial genetics0301 basic medicinemolecular cloningSettore MED/07 - Microbiologia E Microbiologia ClinicaKlebsiella pneumoniaeTransposition (music)Drug Resistance Multiple Bacterialpolycyclic compoundsgenetic screeningcell clonecarbapenem derivativeKlebsiella infectionunclassified drugAnti-Bacterial AgentsInfectious Diseasesbacterial genePlasmidsenzymologydoripenemBiologyminimum inhibitory concentrationbeta-Lactamasesbeta lactamaseMechanisms of ResistanceciprofloxacinAmikacin; aztreonam; carbapenemase; cefepime; cefotaxime; cefoxitin; cefpodoxime; ceftazidime; ceftriaxone; ciprofloxacin; colistin; cotrimoxazole; doripenem; doxycycline; ertapenem; gentamicin; imipenem; Klebsiella pneumoniae carbapenemase 3; levofloxacin; meropenem; minocycline; piperacillin plus tazobactam; plasmid DNA; polymyxin B; tigecycline; timentin; tobramycin; unclassified drug; antiinfective agent; bacterial protein; beta lactamase; carbapenem derivative; transposon antibiotic sensitivity; Article; bacterial gene; bacterial genetics; bacterial strain; bacterium; bacterium detection; bacterium isolation; Escherichia coli; extensively drug resistant bacterium; gene dosage; genetic screening; Italy; Klebsiella pneumoniae; Klebsiella pneumoniae carbapenemase 3 producing Klebsiella pneumoniae; minimum inhibitory concentration; molecular cloning; nonhuman; polymerase chain reaction; priority journal; sequence analysis; cell clone; chemistry; drug effects; enzymology; gene expression regulation; genetics; isolation and purification; Klebsiella infection; Klebsiella pneumoniae; metabolism; microbial sensitivity test; microbiology; multidrug resistance; open reading frame; plasmid; transposon Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Clone Cells; DNA Transposable Elements; Drug Resistance Multiple Bacterial; Gene Dosage; Gene Expression Regulation Bacterial; Italy; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Open Reading Frames; Plasmidsplasmidbacterium isolationEscherichia coliGeneAmikacinbacterium detectionnonhumandoxycyclineisolation and purificationGene Expression Regulation Bacterialbiology.organism_classificationbacterial straincotrimoxazoleOpen reading frameDNA Transposable Elementdrug effectsDNA Transposable Elementsmetabolismaztreonamimipenem
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2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

2020

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

unstable anginaMyocardial ischaemia[SDV]Life Sciences [q-bio]Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]dual antithrombotic therapyGuidelineheparin030204 cardiovascular system & hematologyPlatelet inhibitionantiplatelet0302 clinical medicineST segmentMedicinedabigatranMyocardial infarctionguidelinesglycoprotein iib/iiia inhibitorsanticoagulationNon-ST Elevated Myocardial InfarctionrivaroxabanComputingMilieux_MISCELLANEOUSreproductive and urinary physiologydiabetesbleedingsbivalirudinatherothrombosiDisease ManagementangioplastyGuidelines • acute cardiac care • acute coronary syndrome • angioplasty • anticoagulation • antiplatelet • apixaban • aspirin • atherothrombosis • betablockers • bleedings • bivalirudin • bypass surgery • cangrelor • chest pain unit • clopidogrel • dabigatran • diabetes • dual antithrombotic therapy • early invasive strategy • edoxaban • enoxaparin • European Society of Cardiology • fondaparinux • glycoprotein IIb/ IIIa inhibitors • heparin • high-sensitivity troponin • minoca • myocardial ischaemia • myocardial infarction • nitrates • non-ST-elevation myocardial infarction • platelet inhibition • prasugrel • recommendations • revascularization • rhythm monitoring • rivaroxaban • stent • ticagrelor • triple therapy • unstable anginaenoxaparinGeneral MedicineClopidogrel3. Good healthearly invasive strategymyocardial infarctiontriple therapy030220 oncology & carcinogenesisHigh sensitivity troponinembryonic structuresCardiologyPlatelet aggregation inhibitorrevascularizationbiological phenomena cell phenomena and immunityCardiology and Cardiovascular MedicineTicagrelormedicine.drugHumanrecommendationAcute coronary syndromemedicine.medical_specialtyaspiringlycoprotein IIb/IIIa inhibitornon-ST-elevation myocardial infarctionapixabanrhythm monitoringEuropean Society of Cardiologyticagrelor03 medical and health sciencesnitrateatherothrombosisbetablockersInternal medicineacute cardiac careminocachest pain unitDiseases of the circulatory (Cardiovascular) systemHumansIn patientAcute Coronary SyndromeclopidogrelUnstable anginaurogenital systemnitratesbusiness.industryfondaparinuxbetablockerArrhythmias Cardiac030229 sport sciencesbleedingmedicine.diseasemyocardial ischaemiaplatelet inhibitionprasugreldiabeteGlycoprotein IIb/IIIa inhibitorsRC666-701bypass surgerySettore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARErecommendationsedoxabanhigh-sensitivity troponinstentbusinessPlatelet Aggregation Inhibitorscangrelor
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Antibacterial activity and cytotoxicity of selected Egyptian medicinal plants.

2011

Medicinal plants have been used as a source of remedies since ancient times in Egypt. The present study was designed to investigate the antibacterial activity and the cytotoxicity of the organic extracts from 16 selected medicinal plants of Egypt. The study was also extended to the isolation of the antiproliferative compound jaeschkeanadiol p-hydroxybenzoate (FH-25) from Ferula hermonis. The microbroth dilution was used to determine the minimal inhibitory concentration (MIC) of the samples against twelve bacterial strains belonging to four species, Providencia stuartii, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli, while a resazurin assay was used to assess the cytoto…

ved/biology.organism_classification_rank.speciesPharmaceutical ScienceBreast NeoplasmsMicrobial Sensitivity TestsProvidenciamedicine.disease_causeAnalytical Chemistrychemistry.chemical_compoundMinimum inhibitory concentrationInhibitory Concentration 50MagnoliopsidaCell Line TumorKlebsiellaPseudomonasDrug DiscoverymedicineEscherichia coliHumansVitisCytotoxicityMedicinal plantsEscherichia coliPharmacologyLeukemiaPlants MedicinalbiologyTraditional medicineved/biologyPlant ExtractsProvidencia stuartiiOrganic ChemistryResazurinbiology.organism_classificationAntineoplastic Agents PhytogenicAnti-Bacterial AgentsFerulaComplementary and alternative medicinechemistryDrug Resistance NeoplasmMolecular MedicineEgyptFemaleAntibacterial activitySesquiterpenesFerula hermonisPhytotherapyPlanta medica
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In-Depth Characterization of Bioactive Extracts from Posidonia oceanica Waste Biomass

2019

© 2019 by the authors.

ved/biology.organism_classification_rank.speciesPhytochemicalsPharmaceutical ScienceBiomassMicrobiologiaantioxidant capacity7. Clean energy01 natural sciencesEcologia marinaAntioxidantsFoodborne Diseaseschemistry.chemical_compoundMicevalorisationAnti-Infective AgentsDrug DiscoveryFood scienceAntifungal activityBiomasslcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Caliciviridae InfectionsPlant Proteinschemistry.chemical_classificationFeline calicivirusAlismatalesbiologyultrasound04 agricultural and veterinary sciences040401 food scienceantiviralLipids6. Clean waterAntioxidant capacityMicrobiologia marinaPosidonia oceanicaMitosporic FungiValorisationValorisationMicrobial Sensitivity TestsPolysaccharideArticle0404 agricultural biotechnologyPhenolsPolysaccharidesUltrasoundAnimalsHumansAntiviralHot water extractionEthanolEthanol010405 organic chemistryved/biologyPlant Extractsantifungal activityNorovirusWaterbiology.organism_classification0104 chemical sciencesEcologiaHot water extractionRAW 264.7 Cellslcsh:Biology (General)chemistryCatsSolventsAntiviralesQuímica Analíticahot water extractionMurine norovirusCalicivirus FelineMarine Drugs
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Characterization and antimicrobial activity of the volatile components of the flowers of Magydaris tomentosa (Desf.) DC. collected in Sicily and Alge…

2014

The essential oils of the flowers of Magydaris tomentosa (Desf.) DC. (Apiaceae) collected in Sicily (MSi) and Algeria (MAl), respectively, were obtained by hydrodistillation, and their compositions were analysed. The analyses allowed the identification and quantification of 23 components in MSi and 60 compounds in MAl, respectively, showing a very different profile in the composition of the two populations. The main components of MSi were cembrene (28.2%), α-springene (17.5%) and β-springene (14.8%), also present in MAl but in lesser amount (0.4%, 1.8% and 0.9%, respectively), whereas the principal constituents of MAl were (E)-nerolidol (35.4%), α-costol (13.3%) and β-costol (6.8%). Both MS…

β-springeneFlowersMicrobial Sensitivity TestsPlant ScienceBiochemistryMagydaris tomentosaGas Chromatography-Mass Spectrometryessential oilAnalytical ChemistryAnti-Infective Agentsα\-springeneStaphylococcus epidermidisparasitic diseasesOils VolatileMagydarisSicilyApiaceaeantimicrobial activitybiologyTraditional medicineOrganic ChemistrySettore CHIM/06 - Chimica Organicabiology.organism_classificationAntimicrobialαspringeneAnti-Bacterial AgentsPlant LeavesChemotaxonomyAlgerialipids (amino acids peptides and proteins)Composition (visual arts)DiterpenesAntibacterial activitySesquiterpenesApiaceae
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